Practical Synthesis of Cytidine-5-Carboxamide-Modified Nucleotide Reagents
نویسندگان
چکیده
منابع مشابه
Practical Synthesis of Cytidine-5-Carboxamide-Modified Nucleotide Reagents
Chemically-modified derivatives of cytidine, bearing a 5-(N-substituted-carboxamide) functional group, are new reagents for use in aptamer discovery via the SELEX process (Systematic Evolution of Ligands by EXponential enrichment). Herein, we disclose a practical synthesis of 5-(N-benzylcarboxamide)-2'-deoxycytidine, and the corresponding 5-(N-1-naphthylmethylcarboxamide)- and 5-(N-3-phenylprop...
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ژورنال
عنوان ژورنال: Nucleosides, Nucleotides and Nucleic Acids
سال: 2015
ISSN: 1525-7770,1532-2335
DOI: 10.1080/15257770.2014.978011